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This week on the Daily Beat: We look at the scientific methods that are in need of re-evaluation.
Today on the Daily Beat, Monday December 14, 2015: Dr. Azra Raza, the Director of the MDS Center at Columbia University in New York, NY, speaks with us about finding alternatives to the mouse model used in drug development research.
We cured acute leukemia in mice in 1977 with drugs that we are still using in exactly the same dose and duration today in humans with dreadful results. A recent scientific paper showed that all 150 drugs tested at the cost of billions of dollars in human trials of sepsis failed because the drugs had been developed using mice. Unfortunately, what looks like sepsis in mice turned out to be very different than what sepsis is in humans. Coverage of this study by Gina Kolata in the New York Times incited a heated response from within the biomedical research community
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